{"id":1508,"date":"2014-07-17T17:35:04","date_gmt":"2014-07-17T08:35:04","guid":{"rendered":"http:\/\/150.60.187.158\/taka\/2014\/07\/17\/ctl019\/"},"modified":"2014-07-17T17:35:04","modified_gmt":"2014-07-17T08:35:04","slug":"ctl019","status":"publish","type":"post","link":"https:\/\/www.oceanbridge.jp\/taka\/archives\/2014\/07\/ctl019.html","title":{"rendered":"\u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5\u306e\u753b\u671f\u7684\u306a\u7d30\u80de\u533b\u85ac\u300cCTL019\u300d\u304c\u30a2\u30e1\u30ea\u30ab\u3067\u30b9\u30d4\u30fc\u30c9\u627f\u8a8d\u3055\u308c\u308b\u304b\uff1f"},"content":{"rendered":"<p>\u5148\u65e5\u3001\u3053\u3093\u306a\u8a18\u4e8b\u3092\u898b\u3064\u3051\u307e\u3057\u305f\u3002<br \/>\n<a href=\"http:\/\/medical.nikkeibp.co.jp\/leaf\/mem\/pub\/search\/cancer\/news\/201407\/537428.html\">\u25bc\u30c6\u30a4\u30e9\u30fc\u30e1\u30fc\u30c9\u306eALL\u6cbb\u7642\u7528\u7d30\u80de\u533b\u85acCTL019\u304c\u7c73\u56fd\u3067\u753b\u671f\u7684\u6cbb\u7642\u85ac\u306b\u6307\u5b9a\uff1a\u65e5\u7d4c\u30e1\u30c7\u30a3\u30ab\u30eb<\/a>\uff08\u8a18\u4e8b\u5168\u6587\u3092\u8aad\u3080\u306b\u306f\u7121\u6599\u4f1a\u54e1\u767b\u9332\u304c\u5fc5\u8981\u3067\u3059\uff09<\/p>\n<p><!--more--><\/p>\n<blockquote><p>\u3000\u30b9\u30a4\u30b9Novartis\u793e\u306f\u30012014\u5e747\u67087\u65e5\u3001\u7c73\u98df\u54c1\u533b\u85ac\u54c1\u5c40\uff08FDA\uff09\u304c\u3001\u5c0f\u5150\u3068\u6210\u4eba\u306e\u518d\u767a\u6027\/\u96e3\u6cbb\u6027\u6025\u6027\u30ea\u30f3\u30d1\u82bd\u6025\u6027\u767d\u8840\u75c5\uff08r\/rALL\uff09\u3092\u9069\u5fdc\u3068\u3057\u3066\u3001\u60a3\u8005\u81ea\u8eab\u306eT\u7d30\u80de\u3092\u907a\u4f1d\u7684\u306b\u4fee\u98fe\u3057\u3066\u672c\u4eba\u306b\u623b\u3059\u514d\u75ab\u7d30\u80de\u6cbb\u7642CTL019\u3092\u753b\u671f\u7684\u6cbb\u7642\u85ac\u306b\u6307\u5b9a\u3057\u305f\u3068\u767a\u8868\u3057\u305f\u3002<\/p><\/blockquote>\n<p>\u50d5\u3068\u540c\u3058\u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5\u3067\u3001\u518d\u767a\u3057\u305f\u5834\u5408\u3001\u307e\u305f\u306f\u96e3\u6cbb\u6027\u306e\u5834\u5408\u306b\u9069\u5fdc\u3068\u306a\u308b\u753b\u671f\u7684\u306a\u6cbb\u7642\u304c\u3001\u30a2\u30e1\u30ea\u30ab\u3067\u8fd1\u3044\u5c06\u6765\u627f\u8a8d\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3001\u3068\u306e\u3053\u3068\u3002\u50d5\u3082\u542b\u3081\u3066\u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5\u306e\u60a3\u8005\u3055\u3093\u306b\u306f\u8208\u5473\u6df1\u3044\u30cb\u30e5\u30fc\u30b9\u3067\u3059\u3002<\/p>\n<blockquote><p>\u60a3\u8005\u81ea\u8eab\u306eT\u7d30\u80de\u3092\u63a1\u53d6\u3057\u3001T\u7d30\u80de\u53d7\u5bb9\u4f53\uff08TCR\uff09\u306e\u4ee3\u308f\u308a\u306b\u3001\u6297CD19\u6297\u4f53\u7531\u6765\u306e\u30ea\u30ac\u30f3\u30c9\u9818\u57df\u3092\u6301\u3064CAR\u3092\u7d44\u307f\u8fbc\u307f\u3001\u816b\u760d\u7d30\u80de\u3092\u7279\u7570\u7684\u306b\u7834\u58ca\u3059\u308b\u7d30\u80de\u533b\u85acCTL019\u3068\u3057\u3066\u60a3\u8005\u306b\u623b\u3059\u3002\u60a3\u8005\u306e\u4f53\u5185\u3067CTL019\u306f\u5897\u6b96\u3057\u3001CD19\u967d\u6027\u60aa\u6027\u7d30\u80de\u306b\u7d50\u5408\u3057\u3066\u305d\u308c\u3089\u3092\u7834\u58ca\u3059\u308b\u3002<\/p><\/blockquote>\n<p>\u3064\u307e\u308a\u3001\u60a3\u8005\u81ea\u8eab\u306eT\u7d30\u80de\u3092\u53d6\u308a\u51fa\u3057\u3066\u3001\u907a\u4f1d\u7684\u306b\u624b\u3092\u52a0\u3048\u3066\u672c\u4eba\u306e\u4f53\u5185\u306b\u623b\u3059\u3068\u3001\u305d\u306e\u6539\u9020\u3055\u308c\u305fT\u7d30\u80de\u304c\u3001\u304c\u3093\u7d30\u80de\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3057\u3066\u653b\u6483\u3057\u3066\u3084\u3063\u3064\u3051\u3066\u304f\u308c\u308b\u3001\u3068\u3044\u3046\u3053\u3068\u306e\u3088\u3046\u3067\u3059\u3002<\/p>\n<blockquote><p>\u753b\u671f\u7684\u6cbb\u7642\u85ac\u6307\u5b9a\u306f\u30012012\u5e74\u306eFDA Safety and Innovation Act\uff08FDASIA\uff09\u306e\u4e00\u90e8\u3068\u3057\u3066\u5236\u5b9a\u3055\u308c\u305f\u3082\u306e\u3067\u3001\u91cd\u7be4\u3082\u3057\u304f\u306f\u81f4\u547d\u7684\u306a\u75be\u60a3\u3092\u5bfe\u8c61\u3068\u3059\u308b\u6cbb\u7642\u85ac\u3092\u3088\u308a\u65e9\u304f\u60a3\u8005\u306e\u5143\u306b\u5c4a\u3051\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u3044\u308b\u3002<\/p><\/blockquote>\n<blockquote><p>\u3053\u306e\u30d7\u30ed\u30b0\u30e9\u30e0\u306f\u3001\u958b\u767a\u3057\u305f\u4f1a\u793e\u304c\u3001\u78ba\u304b\u306a\u52b9\u679c\u3092\u78ba\u8a8d\u3059\u308b\u8a66\u9a13\u3092\u884c\u3063\u3066\u3044\u308b\u9593\u306b\u3001\u65b0\u305f\u306a\u6cbb\u7642\u85ac\u3092\u5fc5\u8981\u3068\u3059\u308b\u60a3\u8005\u3078\u306e\u85ac\u5264\u306e\u63d0\u4f9b\u3092\u53ef\u80fd\u306b\u3059\u308b\u3002<\/p><\/blockquote>\n<p>\u901a\u5e38\u3067\u3042\u308c\u3070\u3001\u65b0\u85ac\u3084\u65b0\u3057\u3044\u6cbb\u7642\u306e\u81e8\u5e8a\u8a66\u9a13\u3084\u627f\u8a8d\u30d7\u30ed\u30bb\u30b9\u306b\u306f\u3001\u5e74\u5358\u4f4d\u306e\u6642\u9593\u304c\u304b\u304b\u308b\u3082\u306e\u3067\u3059\u304c\u3053\u306e\u300c\u753b\u671f\u7684\u6cbb\u7642\u85ac\u6307\u5b9a\u300d\u3067\u306f\u3001\u305d\u306e\u30d7\u30ed\u30bb\u30b9\u304c\u30b9\u30d4\u30fc\u30c9\u30a2\u30c3\u30d7\u3057\u3001\u3088\u308a\u65e9\u304f\u60a3\u8005\u306b\u5c4a\u3051\u3089\u308c\u308b\u3068\u306e\u3053\u3068\u3002<br \/>\n\u6c17\u306b\u306a\u308b\u306e\u306f\u3001\u3053\u306e\u85ac\u304c\u65e5\u672c\u3067\u306f\u3044\u3064\u9803\u4f7f\u3048\u308b\u3088\u3046\u306b\u306a\u308b\u306e\u304b\u3068\u3044\u3046\u3053\u3068\u3002\u8abf\u3079\u3066\u307f\u305f\u3068\u3053\u308d\u3001\u3053\u3093\u306a\u8a18\u4e8b\u3092\u898b\u3064\u3051\u307e\u3057\u305f\u3002<br \/>\n<a href=\"https:\/\/bio.nikkeibp.co.jp\/article\/news\/20131021\/171546\/\">\u25bcNovartis\u793e\u304c\u7d30\u80de\u533b\u85acCTL019\u306e\u81e8\u5e8a\u8a66\u9a13\u3092\u65e5\u672c\u3067\u3082\u958b\u59cb\u3078\u3001\u958b\u767a\u30c1\u30fc\u30e0\u306b\u306f\u5143\u30ad\u30ea\u30f3\u306e\u300cProvenge\u300d\u62c5\u5f53\u8005\uff1a\u65e5\u7d4c\u30d0\u30a4\u30aa\u30c6\u30afONLINE<\/a><\/p>\n<blockquote><p>\u30b9\u30a4\u30b9Novartis\u793e\u304c\u7d30\u80de\u533b\u85acCTL019\u306e\u65e5\u672c\u3067\u306e\u81e8\u5e8a\u8a66\u9a13\u958b\u59cb\u3092\u8a08\u753b\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u30012013\u5e7410\u670821\u65e5\u307e\u3067\u306b\u672c\u8a8c\u306e\u53d6\u6750\u3067\u5206\u304b\u3063\u305f\u3002<\/p><\/blockquote>\n<p>Novartis\u793e\u306b\u3088\u308b\u3068\u3001<\/p>\n<blockquote><p>\u3067\u304d\u308b\u3060\u3051\u65e9\u671f\u306b\u65e5\u672c\u3067\u3082\u958b\u59cb\u3057\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u308b\u3002\u305f\u3060\u3057\u3001CTL019\u306f\u524d\u4f8b\u306e\u7121\u3044\u88fd\u54c1\u3067\u3042\u308a\u3001\u65e5\u672c\u3067\u306e\u81e8\u5e8a\u8a66\u9a13\u3092\u3044\u3064\u958b\u59cb\u3067\u304d\u308b\u304b\u5177\u4f53\u7684\u306a\u65e5\u7a0b\u306b\u306f\u307e\u3060\u8a00\u53ca\u3067\u304d\u306a\u3044<\/p><\/blockquote>\n<p>\u3068\u3044\u3046\u3053\u3068\u3067\u3001\u65e5\u672c\u3067\u306e\u81e8\u5e8a\u8a66\u9a13\u3082\u3001\u8a08\u753b\u306f\u3055\u308c\u3066\u3044\u308b\u3082\u306e\u306e\u3001\u3044\u3064\u306b\u306a\u308b\u304b\u306f\u307e\u3060\u5206\u304b\u3089\u306a\u3044\u3001\u3068\u3044\u3046\u304b\u307e\u3060\u8a00\u3048\u306a\u3044\u3001\u3068\u3044\u3046\u3053\u3068\u306e\u3088\u3046\u3067\u3059\u3002<br \/>\n\u307e\u3060\u307e\u3060\u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5\uff08B\u7d30\u80de\u6027\u30ea\u30f3\u30d1\u82bd\u7403\u6027\u30ea\u30f3\u30d1\u816b\uff09\u306e\u518d\u767a\u306e\u53ef\u80fd\u6027\u3082\u30bc\u30ed\u3067\u306f\u306a\u3044\u50d5\u3068\u3057\u3066\u3082\u3001\u65e9\u304f\u3053\u306e\u85ac\u304c\u65e5\u672c\u306e\u539a\u751f\u52b4\u50cd\u7701\u306b\u3082\u627f\u8a8d\u3055\u308c\u308b\u3068\u3044\u3044\u306a\u3042\u3068\u671f\u5f85\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u95a2\u9023\u30cb\u30e5\u30fc\u30b9\u3082\u898b\u3064\u3051\u307e\u3057\u305f\u3002<br \/>\n<a href=\"http:\/\/jp.sciencenewsline.com\/articles\/2013120908550036.html\">\u25bc\u30da\u30f3\u30b7\u30eb\u30d0\u30cb\u30a2\u5927\u3001\u767d\u8840\u75c5\u60a3\u8005\u3078\u306e\u521d\u306e\u7d30\u80de\u7642\u6cd5\u306e\u7d50\u679c\u5831\u544a &#8211; ScienceNewsline<\/a><\/p>\n<blockquote><p>\u6025\u6027\u30ea\u30f3\u30d1\u82bd\u7403\u6027\u767d\u8840\u75c5\uff08acute lymphoblastic leukemia\uff09\u306e\u6210\u4eba\u306e\u60a3\u8005\u3068\u5c0f\u5150\u60a3\u8005\u306e\u5834\u5408\u306e\u5b8c\u5168\u5bdb\u89e3\u7387\u306f89\uff05\u3068\u306a\u3063\u305f\u3002<\/p><\/blockquote>\n<blockquote><p>\u4eba\u9593\u306e\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u3068\u4eba\u70ba\u7684\u306b\u64cd\u4f5c\u3055\u308c\u305f\u72e9\u731f\u7d30\u80de\uff08hunter cells\uff09\u306e\u4e21\u65b9\u304c\u5354\u8abf\u3057\u3066\u6a5f\u80fd\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u816b\u760d\u306b\u5bfe\u3057\u3066\u307e\u3063\u305f\u304f\u65b0\u3057\u3044\u65b9\u6cd5\u3067\u653b\u6483\u3092\u884c\u3046<\/p><\/blockquote>\n<p><a href=\"http:\/\/www.gizmodo.jp\/2012\/12\/hiv.html\">\u25bc\u767d\u8840\u75c5\u306e\u5c11\u5973\u3001HIV\u30a6\u30a4\u30eb\u30b9\u3092\u4f7f\u3063\u305f\u6cbb\u7642\u6cd5\u3067\u56de\u5fa9 : \u30ae\u30ba\u30e2\u30fc\u30c9\u30fb\u30b8\u30e3\u30d1\u30f3<\/a><\/p>\n<blockquote><p>\u3053\u306e\u6cbb\u7642\u3067\u306f\u3001\u307e\u305a\u60a3\u8005\u306eT\u7d30\u80de\u3092\u4f53\u304b\u3089\u6570\u767e\u4e07\u500b\u53d6\u308a\u51fa\u3057\u3001\u305d\u3053\u306b\u304c\u3093\u3068\u6226\u3046\u305f\u3081\u306e\u907a\u4f1d\u5b50\u3092\u633f\u5165\u3059\u308b\u306e\u3067\u3059\u304c\u3001\u305d\u306e\u969b\u306b\u7121\u52b9\u5316\u3055\u308c\u305fHIV\u30a6\u30a4\u30eb\u30b9\u304c\u4f7f\u308f\u308c\u307e\u3059\u3002\u305d\u306eT\u7d30\u80de\u304c\u60a3\u8005\u306e\u8840\u7ba1\u306b\u623b\u3055\u308c\u3001\u4f53\u5185\u3067\u304c\u3093\u3068\u6226\u3046\u306e\u3067\u3059\u3002\u305d\u306e\u969b\u306e\u60a3\u8005\u306e\u8ca0\u62c5\u306f\u5927\u304d\u304f\u3001\u6fc0\u3057\u3044\u9ad8\u71b1\u3068\u60aa\u5bd2\u304c\u3042\u308a\u307e\u3059\u3002<\/p><\/blockquote>\n<blockquote><p>\u3067\u3082\u3001\u7814\u7a76\u30c1\u30fc\u30e0\u306e\u30ea\u30fc\u30c0\u30fc\u3001\u30ab\u30fc\u30eb\u30fb\u30b8\u30e5\u30fc\u30f3\uff08Carl June\uff09\u535a\u58eb\u306f\u3001\u300c\u6cbb\u7652\uff08cure\uff09\u300d\u3068\u3044\u3046\u8a00\u8449\u306f\u3053\u306e\u6cbb\u7642\u306b\u5bfe\u3057\u3066\u306f\u4f7f\u308f\u306a\u3044\u3068\u30cb\u30e5\u30fc\u30e8\u30fc\u30af\u30fb\u30bf\u30a4\u30e0\u30ba\u306b\u8a9e\u3063\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u73fe\u5728\u306f\u304c\u3093\u306e\u75c7\u72b6\u304c\u51fa\u3066\u3044\u306a\u304f\u3066\u3082\u3001\u305d\u308c\u3067\u300c\u5b8c\u6cbb\u3057\u305f\u300d\u3068\u306f\u307e\u3060\u8a00\u3048\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u304c\u3001\u535a\u58eb\u306f\u300c\u4eca\u5f8c\u9aa8\u9ac4\u79fb\u690d\u306b\u4ee3\u308f\u308b\u6cbb\u7642\u6cd5\u306b\u3067\u304d\u308c\u3070\u300d\u3068\u5e0c\u671b\u3092\u8a9e\u3063\u3066\u3082\u3044\u307e\u3059\u3002<\/p><\/blockquote>\n<p>\u307e\u3060\u307e\u3060\u526f\u4f5c\u7528\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306a\u3069\u3001\u8ab2\u984c\u3082\u591a\u3044\u3088\u3046\u3067\u3059\u304c\u3001\u3053\u306e\u535a\u58eb\u304c\u8a00\u3046\u3088\u3046\u306b\u3001\u3044\u305a\u308c\u9aa8\u9ac4\u79fb\u690d\u306b\u4ee3\u308f\u308b\u6cbb\u7642\u306b\u306a\u3063\u3066\u304f\u308c\u305f\u3089\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5148\u65e5\u3001\u3053\u3093\u306a\u8a18\u4e8b\u3092\u898b\u3064\u3051\u307e\u3057\u305f\u3002 \u25bc\u30c6\u30a4\u30e9\u30fc\u30e1\u30fc\u30c9\u306eALL\u6cbb\u7642\u7528\u7d30\u80de\u533b\u85acCTL019\u304c\u7c73\u56fd\u3067\u753b\u671f\u7684\u6cbb\u7642\u85ac\u306b\u6307\u5b9a\uff1a\u65e5\u7d4c\u30e1\u30c7\u30a3\u30ab\u30eb\uff08\u8a18\u4e8b\u5168\u6587\u3092\u8aad\u3080\u306b\u306f\u7121\u6599\u4f1a\u54e1\u767b\u9332\u304c\u5fc5\u8981\u3067\u3059\uff09<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"close","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[34],"tags":[],"class_list":["post-1508","post","type-post","status-publish","format-standard","hentry","category-cat126"],"aioseo_notices":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.oceanbridge.jp\/taka\/wp-json\/wp\/v2\/posts\/1508","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.oceanbridge.jp\/taka\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.oceanbridge.jp\/taka\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.oceanbridge.jp\/taka\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.oceanbridge.jp\/taka\/wp-json\/wp\/v2\/comments?post=1508"}],"version-history":[{"count":0,"href":"https:\/\/www.oceanbridge.jp\/taka\/wp-json\/wp\/v2\/posts\/1508\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.oceanbridge.jp\/taka\/wp-json\/wp\/v2\/media?parent=1508"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.oceanbridge.jp\/taka\/wp-json\/wp\/v2\/categories?post=1508"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.oceanbridge.jp\/taka\/wp-json\/wp\/v2\/tags?post=1508"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}